The Apothecary Diaries Guide: Every Episode, Cast and Where to Stream

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The Apothecary Diaries key art
The Apothecary Diaries poster art

Series guide

The Apothecary Diaries
  • TV Series
  • 2023-2025
  • Nippon Television
Stars
Aoi Yūki · Takeo Ōtsuka · Atsumi Tanezaki

Images: Crunchyroll

Where to watch The Apothecary Diaries

Streaming options in the United States, updated Sep 15, 2026. More from crunchyroll.com. Service logos are trademarks of their owners.

Episodes aired
48 of 48

Seasons 2

The Apothecary Diaries episodes 48

Season

Season 1 · 24 episodes · 24 aired · Oct 22, 2023 to Mar 24, 2024

  1. E1Oct 22
  2. E2Oct 22
  3. E3Oct 22
  4. E4Oct 29
  5. E5Nov 6
  6. E6Nov 12
  7. E7Nov 19
  8. E8Nov 26
  9. E9Dec 3
  10. E10Dec 10
  11. E11Dec 17
  12. E12Dec 24
  13. E13Jan 7
  14. E14Jan 14
  15. E15Jan 21
  16. E16Jan 28
  17. E17Feb 4
  18. E18Feb 11
  19. E19Feb 18
  20. E20Feb 25
  21. E21Mar 3
  22. E22Mar 10
  23. E23Mar 17
  24. E24Mar 24
  1. S1.E1 ·

    Maomao

    Kidnapped by bandits and sold into the emperor's rear palace as a laundry maid, apothecary's daughter Maomao hears that a curse is sickening the infants of two rival concubines.

    Directed by Akinori Fudesaka · Written by Yūko Kakihara

  2. S1.E2 ·

    Chilly Apothecary

    Settling in as Gyokuyou's food taster, Maomao is handed two odd jobs by Jinshi: explain how a village's soldiers were poisoned at dinner, and brew him an aphrodisiac.

    Directed by Kentarō Fujita · Written by Misuzu Chiba

  3. S1.E3 ·

    The Unsettling Matter of the Spirit

    A pale woman is said to dance along the eastern wall by moonlight, so Gaoshun and Maomao go looking for the concubine behind the palace's newest ghost story.

    Directed by Kyohei Yamamoto · Written by Hitomi Ogawa

  4. S1.E4 ·

    The Threat

    The emperor asks Maomao to nurse Consort Lihua, whose illness has outlasted every treatment, but the consort's protective attendants keep throwing her out of the sickroom.

    Directed by China (director) · Written by Yūko Kakihara

  5. S1.E5 ·

    Covert Operations

    A patient turns up at the clinic begging for a cure for a curse, just as Maomao is swept into preparations for a garden party where the emperor's highest consorts will all attend.

    Directed by Gaku Shiga · Written by Misuzu Chiba

  6. S1.E6 ·

    The Garden Party

    Stuck among sniping ladies-in-waiting at the garden party, Maomao collects gossip about a rift between Ah-Duo and Lishu, then tastes something in Gyokuyou's soup that should not be there.

    Directed by Wataru Nakagawa · Written by Hitomi Ogawa

  7. S1.E7 ·

    Homecoming

    Back on her feet after the party, Maomao borrows the silver soup bowl and a few brothel tricks to work out whose hands touched it, then bargains a hairpin into a trip home.

    Directed by Tadao Ōkubo · Written by Yūko Kakihara

  8. S1.E8 ·

    Wheat Stalks

    A panicked servant girl hammers on the apothecary's door and drags Maomao to a brothel, where a courtesan and a well-dressed customer both lie slumped and poisoned.

    Directed by Kentarō Fujita · Written by Yuniko Ayana

  9. S1.E9 ·

    Suicide or Murder?

    Kounen, a high-ranking official, dies after a night of hard drinking, and a servant woman is pulled from the moat, leaving Maomao two deaths and no clean explanation for either.

    Directed by Akira Koremoto · Written by Misuzu Chiba

  10. S1.E10 ·

    Honey

    Gossip about the drowned servant spreads while Maomao sits through a tea party where Lishu flinches from honeyed tea, and Jinshi quietly sends her on to attend Consort Ah-Duo.

    Directed by Erkin Kawabata · Written by Hitomi Ogawa

  11. S1.E11 ·

    Reducing Two to One

    Maomao puts to Fengming what she has pieced together about Ah-Duo's lost child, the doctor expelled from the palace, and the poison that was never meant for Gyokuyou.

    Directed by Yukihiko Asaki · Written by Yūko Kakihara

  12. S1.E12 ·

    The Eunuch and the Courtesan

    A palace purge sweeps up Maomao over her ties to a trafficking ring, costing her her post and sending her back to the Verdigris brothel while Jinshi wrestles with letting her go.

    Directed by Mitsuyo Yokono · Written by Misuzu Chiba

  13. S1.E13 ·

    Serving in the Outer Court

    Reinstated in the outer court rather than the rear palace, Maomao flunks the court lady exams, lands as Jinshi's personal assistant, and draws the glares of jealous court ladies.

    Directed by Wataru Nakagawa · Written by Yuniko Ayana

  14. S1.E14 ·

    The New Pure Consort

    Handed the job of teaching new Pure Consort Loulan how to please the emperor, Maomao is pulled away by an explosion that tears through a palace storehouse overnight.

    Directed by Akira Shimizu & Jun Ōwada · Written by Hitomi Ogawa

  15. S1.E15 ·

    Raw Fish

    A bureaucrat falls into a coma after a meal of raw fugu, echoing an identical case ten years earlier, and Gaoshun asks Maomao to find the one detail that does not fit.

    Directed by Kentarō Fujita · Written by Yūko Kakihara

  16. S1.E16 ·

    Lead

    A metalworker's will leaves his three sons a workshop, a locked chest with one drawer that will not open, and a glass fishbowl, and Maomao is sent to make sense of it.

    Directed by So Toyama · Written by Misuzu Chiba

  17. S1.E17 ·

    A Jaunt Around Town

    Jinshi wants to stroll through town unrecognized, which means asking Maomao to make the most beautiful man in the palace look thoroughly ordinary.

    Directed by Kurabu Kadomatsu · Written by Yuniko Ayana

  18. S1.E18 ·

    Lakan

    A few days off take Maomao home to an errand at the Verdigris annex and an old nightmare, while back at the palace an official named Lakan takes a pointed interest in her.

    Directed by Mayu Tanimoto & Jun Ōwada · Written by Hitomi Ogawa

  19. S1.E19 ·

    Chance or Something More

    Lihaku mentions tools stolen around the night of the warehouse fire, and the ivory pipe Maomao found there starts linking a poisoning, a drinker's death, and Jinshi's purification rites.

    Directed by Wataru Nakagawa · Written by Yūko Kakihara

  20. S1.E20 ·

    Thornapple

    Waking in Jinshi's room, Maomao walks Basen, Gaoshun and Jinshi through the single ceremonial tool that ties a warehouse fire, two poisonings and a theft together.

    Directed by Akira Koremoto · Written by Misuzu Chiba

  21. S1.E21 ·

    How to Buy Out a Contract

    Maomao takes over scrubbing out the rear-palace pharmacy just as Lihaku comes to her for advice on buying out Pairin, the courtesan who nursed her as a baby.

    Directed by Yūshi Ibe · Written by Yuniko Ayana

  22. S1.E22 ·

    Blue Roses

    Lakan demands blue roses in time for next spring's party, so Jinshi passes the impossible order to Maomao, who commandeers Lihua's sauna and a hundred rosebushes.

    Directed by Erkin Kawabata · Written by Hitomi Ogawa

  23. S1.E23 ·

    Balsam and Woodsorrel

    Maomao challenges Lakan to Chinese chess with her own freedom as the stake, and a cup of liquor laced so that the loser's third sip turns to poison.

    Directed by Jun Ōwada · Written by Misuzu Chiba

  24. S1.E24 ·

    Jinshi and Maomao

    Summoned by the Verdigris madam to finally choose a courtesan for himself, Lakan hesitates over the pick, while Maomao tries on a gift dress atop the rear-palace wall.

    Directed by Wataru Nakagawa · Written by Yūko Kakihara

Season 2 · 24 episodes · 24 aired · Jan 10, 2025 to Jul 4, 2025

  1. E1Jan 10
  2. E2Jan 17
  3. E3Jan 24
  4. E4Jan 31
  5. E5Feb 7
  6. E6Feb 14
  7. E7Feb 21
  8. E8Feb 28
  9. E9Mar 7
  10. E10Mar 14
  11. E11Mar 21
  12. E12Mar 28
  13. E13Apr 4
  14. E14Apr 11
  15. E15Apr 18
  16. E16Apr 25
  17. E17May 2
  18. E18May 9
  19. E19May 23
  20. E20May 31
  21. E21Jun 6
  22. E22Jun 13
  23. E23Jun 27
  24. E24Jul 4
  1. S2.E1 ·

    Maomao and Maomao

    Loulan's swollen retinue unsettles the other consorts, Maomao pushes reading lessons on the servants, and a stray kitten in the garden outruns everyone but one unfamiliar girl.

    Directed by Jun Ōwada · Written by Yūko Kakihara

  2. S2.E2 ·

    Caravan

    With a trading caravan in town and scented oils becoming the court's new craze, Maomao starts checking which fashionable perfumes are safe to keep near a pregnant Gyokuyou.

    Directed by Mayu Tanimoto & Akira Koremoto · Written by Misuzu Chiba

  3. S2.E3 ·

    Corpse Fungus

    Jinshi looks into the death of the palace woman Jin while Maomao, sent to clear poisonous mushrooms from the northern forest, catches the strange smell Shisui described.

    Directed by Wataru Nakagawa · Written by Hitomi Ogawa

  4. S2.E4 ·

    Mirror

    Gaoshun brings Maomao a puzzle about two closely watched twin sisters, one of them somehow pregnant, while a foreign envoy hunts for a woman said to weep pearls.

    Directed by Tsuyoshi Nakano · Written by Yūko Kakihara

  5. S2.E5 ·

    The Moon Fairy

    Shisui's caterpillars turn into moths that glow strangely by moonlight, and the envoys' banquet ends with a lone figure dancing in the dark ringed by drifting lights.

    Directed by Shintaro Itoga · Written by Misuzu Chiba

  6. S2.E6 ·

    The Crystal Pavilion, For the Third Time

    Clinic supervisor Shenlü asks Maomao to track down a servant from Lihua's pavilion who has been missing two weeks and shows every sign of tuberculosis.

    Directed by Yukihiko Asaki · Written by Hitomi Ogawa

  7. S2.E7 ·

    The Shrine of Choosing

    The emperor takes Jinshi and Maomao to the abandoned Shrine of Choosing, where a test once picked emperors and nobody left alive remembers how it was passed.

    Directed by Wazuka Komamiya · Written by Yūko Kakihara

  8. S2.E8 ·

    The Empress Dowager

    Empress Dowager Anshi seeks Maomao out with an unnerving request: find out whether she cursed the late emperor, whose body is said not to have decayed in its tomb.

    Directed by Jun Ōwada · Written by Misuzu Chiba

  9. S2.E9 ·

    The Late Emperor

    Maomao is let into the late emperor's sealed residence, where a poisonous pebble sits among Jinshi's old toys and the air carries an odd, persistent smell.

    Directed by Akira Koremoto · Written by Hitomi Ogawa

  10. S2.E10 ·

    A Ghost Story

    Invited to a night of ghost stories, Maomao listens to a tale of a mother and son shunned after hunger drove them into a forbidden forest, and starts feeling dizzy.

    Directed by Oh Jin Koo · Written by Yūko Kakihara

  11. S2.E11 ·

    The Hunt

    A hunting trip north gives Jinshi his chance to finally tell Maomao who he really is, until the heat of the banquet and a shot from the trees derail him.

    Directed by Shintaro Itoga · Written by Misuzu Chiba

  12. S2.E12 ·

    Ka Zuigetsu

    A search party combs the forest for the missing Jinshi, and Maomao offers to work out who sent the assassins before the trail and the smell of gunpowder go cold.

    Directed by Masahiro Matsunaga · Written by Hitomi Ogawa

  13. S2.E13 ·

    The Baths

    Xiaolan's term is ending with no job to follow it, so Maomao and Shisui take up work in the rear-palace baths, where gossip and useful connections both flow freely.

    Directed by Mayu Tanimoto · Written by Yūko Kakihara

  14. S2.E14 ·

    The Dancing Ghost

    A laughing white face is said to appear in the steam of Lishu's bathhouse, and Maomao, Jinshi and Gaoshun go to see what her contemptuous attendants will not.

    Directed by Jun Ōwada & Kaho Asai · Written by Misuzu Chiba

  15. S2.E15 ·

    Ice

    When Xiaolan knocks a eunuch's block of ice to the ground, the rare shipment meant for Consort Loulan is ruined, and Maomao promises to salvage it in a borrowed kitchen.

    Directed by Misu Yamaneko · Written by Hitomi Ogawa

  16. S2.E16 ·

    Festering Resentment

    While drafting plain-language warnings about lead makeup and strong scents for the palace school, Maomao is cornered by Suirei, who dangles the resurrection formula at her.

    Directed by Tsuyoshi Nakano · Written by Yūko Kakihara

  17. S2.E17 ·

    Fox Village

    Maomao has vanished, and the only lead is a hurried message she hid in the Jade Pavilion, with one character nobody can read.

    Directed by Shintaro Itoga · Written by Misuzu Chiba

  18. S2.E18 ·

    Lantern Plant

    Gyokuyou's labor begins as Jinshi chases a eunuch who slipped out of the palace after repeated visits to a graveyard of girls used by the late emperor.

    Directed by Erkin Kawabata · Written by Hitomi Ogawa

  19. S2.E19 ·

    Festival

    At the village harvest festival, fox masks painted red and green and a founding myth about western settlers start leading Maomao somewhere she did not expect.

    Directed by Mayu Tanimoto · Written by Yūko Kakihara

  20. S2.E20 ·

    The Stronghold

    Kept at the Shi stronghold to develop an immortality drug, Maomao pieces together the family that runs it and notices how much the household is starting to resemble an army.

    Directed by Akira Koremoto & Yū Kinome · Written by Misuzu Chiba

  21. S2.E21 ·

    Taibon

    Maomao learns what the resurrection drug was really a by-product of, then draws Shenmei's fury onto herself to spare Kyou-u the punishment for a failed escape attempt.

    Directed by Takanori Yano · Written by Hitomi Ogawa

  22. S2.E22 ·

    Royal Guard

    As the royal guard closes on the stronghold and Lakan proposes burying its armory under an avalanche, Maomao is confronted with the plan Shisui has made for herself.

    Directed by Masahiro Matsunaga · Written by Yūko Kakihara

  23. S2.E23 ·

    The Shi Clan

    Jinshi reaches Shishou inside the collapsing stronghold and claims the blame for the assassination attempt, while Loulan leads him on toward Shenmei and Suirei.

    Directed by Wataru Nakagawa & Akinori Fudesaka · Written by Misuzu Chiba

  24. S2.E24 ·

    The Beginning

    With the fighting over, Maomao wakes beside Jinshi and turns straight to the poisoned Shi children and a promise to Shisui she has not yet paid.

    Directed by Jun Ōwada & Kaho Asai · Written by Hitomi Ogawa

Videos 2

  • The Apothecary Diaries | OFFICIAL TRAILERCrunchyroll · YouTube
  • The Apothecary Diaries Season 3 | Official Trailer | CrunchyrollCrunchyroll · YouTube

Where to start, and what the two seasons actually cover

Start at episode 1 and keep going — the two seasons are one continuous story. Crunchyroll’s own series page frames season 1 as Maomao’s life as a palace servant and says season 2 “shifts toward deeper political intrigue.” There is no recap season and no soft reset between them, so the 24-episode split is a broadcast convenience rather than a jumping-on point.

The Apothecary Diaries key art
Official The Apothecary Diaries key art. Image: Crunchyroll

The catch-up math is friendlier than the episode count suggests. Forty-eight episodes at roughly 22 minutes each is about 18 hours — a couple of weeks of evenings. That matters right now because Crunchyroll has posted a season 3 trailer to its own YouTube channel, so the back catalog is the homework rather than the destination.

The Apothecary Diaries poster art
Official The Apothecary Diaries artwork. Image: Crunchyroll

It sits a little apart from the shonen shelf it gets filed next to. Adapted from Natsu Hyuuga’s light novels, it is produced by TOHO Animation STUDIO and OLM, directed by Norihiro Naganuma for season 1 with Akinori Fudesaka joining him for season 2, and its Crunchyroll series page lists it as a 2026 Anime Awards winner. The episodes are built as self-contained puzzles, which is why it reads as a procedural in court dress.

The Apothecary Diaries cast 12

  • Aoi Yūki
    Aoi YūkiMaomao
  • Takeo Ōtsuka
    Takeo ŌtsukaJinshi
  • Atsumi TanezakiLingli
  • Yui Ishikawa
    Yui IshikawaLihua
  • Hina Kino
    Hina KinoLishu
  • Yūko KaidaAh-Duo
  • Misaki KunoXiaolan
  • Katsuyuki Konishi
    Katsuyuki KonishiGaoshun
  • Takuya KirimotoLakan
  • Houko KuwashimaFengxian
  • Hiroshi YanakaLuomen
  • Kenji Akabane
    Kenji AkabaneLihaku
Music
Satoru Kōsaki, Kevin Penkin, Alisa Okehazama
Studios
OLM, Inc.

Photos via Wikimedia Commons. Aoi Yūki: SEGA, CC BY 3.0; Takeo Ōtsuka: Dick Thomas Johnson from Tokyo, Japan, CC BY 2.0; Yui Ishikawa: Dick Thomas Johnson from Tokyo, Japan, CC BY 2.0; Hina Kino: AbemaTV, CC BY 3.0; Katsuyuki Konishi: William Tung from USA, CC BY-SA 2.0; Kenji Akabane: numan ch-ヌーマンチャンネル-【公式】, CC BY-SA 3.0.

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Frequently Asked Questions

Where can I watch The Apothecary Diaries?

The Apothecary Diaries streams on Crunchyroll in the US (subscription), checked September 15, 2026.

How many episodes of The Apothecary Diaries are there?

48 episodes across 2 seasons: season 1 has 24, season 2 has 24.

When did The Apothecary Diaries premiere?

October 22, 2023.

Is The Apothecary Diaries finished?

All 48 episodes have aired; the last one was July 4, 2025.

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Trevor Maddison
Trevor Madison is a Senior Comic Book Article Writer at ComicBookCo.com, where he covers the latest in comics, superhero films, and comic-inspired television. Based in Portland, Oregon, Trevor brings a lifelong passion for storytelling, pop culture, and fandom communities to his work. His writing blends insider knowledge with an approachable tone, making his articles resonate with both hardcore collectors and casual fans. Trevor’s expertise spans across decades of comic history, film adaptations, and industry trends. Whether he’s breaking down the cultural impact of a new Marvel release, revisiting iconic story arcs from DC, or highlighting indie creators pushing the medium forward, Trevor is dedicated to bringing readers thoughtful insights and engaging content. When he’s not writing, you’ll likely find him browsing local comic shops, attending fan conventions, or re-watching his favorite superhero shows.

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